Browsing by Subject "Dose-finding, experimental design, continuation ratio model, nonlinear response functions, phase II clinical trials, bivariate responses"
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Optimal designs for contingent response models with application to toxicity and efficacy
(Issac Newton Institute for Mathematical Sciences, 2011-12)We generalize results in the literature to obtain a general family contingent response models. These models have ternary outcomes constructed from two Bernouli outcomes, where one outcome is only observed if the other ...